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 Paget's Disease of Bone. Symptoms Causes and Treatment Paget's disease of bone also known as osteitis deformans is a chronic medical condition that affects the normal remodeling of bone tissue. This condition is characterized by the excessive breakdown and formation of bone  leading to weakened and deformed bones. In this article we will explore the key aspects of Paget's disease including its symptoms causes and available treatment options. Symptoms of Paget's Disease The symptoms of Paget's disease can vary from person to person and some individuals may be asymptomatic. However when symptoms do occur they can include. 1. Bone Pain  One of the most common symptoms is bone pain which can be mild or severe and typically worsens with activity. 2. Deformities  Over time the affected bones can become deformed  leading to issues like bowing of long bones such as the legs and an enlarged or misshapen skull. ...

Osteogenesis Imperfecta   The Reasons and Available Treatments Osteogenesis Imperfecta  often colloquially termed "BRRITLE BONE DISEASE" is an exceptionally rare genetic disorder that adversely impacts the integrity of bones rendering them highly susceptible to fractures. In this article we aim to provide insight into the origins types symptoms and the spectrum of treatment options offered to individuals afflicted with Osteogenesis Imperfecta. Etiology of Osteogenesis Imperfecta. The root cause of Osteogenesis Imperfecta lies predominantly in genetic mutations affecting collagen synthesis  the pivotal protein in fortifying bone structure. Collagen plays a central role in bolstering bone integrity and any disturbances in its production render bones exceedingly brittle rendering them vulnerable to fractures. OI is generally transmitted through an autosomal dominant inheritance pattern, signifying that if one parent possesses the defective gene...

SHINGLES ( HERPES ZOSTER) scientifically known as herpes zoster is a viral infection that primarily affects the skin and nerves. This condition is caused by the varicella zoster virus (VZV) which is the same virus that causes chickenpox. Understanding shingles involves delving into its causes symptoms risk factors treatment and complications. Causes and Origin Shingles stems from a latent VZV infection. After a person contracts chickenpox the virus doesn't completely leave the body. Instead, it remains dormant in nerve cells near the spinal cord and brain. This virus can reactivate years or even decades later causing shingles. The exact reasons for reactivation are not fully understood but may be linked to a weakened immune system stress aging or other factors. Symptoms Shingles often starts with a tingling burning or itching sensation in a specific area of the skin. This is followed by the development of a characteristic rash. The rash ...