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Osteogenesis Imperfecta   The Reasons and Available Treatments Osteogenesis Imperfecta  often colloquially termed "BRRITLE BONE DISEASE" is an exceptionally rare genetic disorder that adversely impacts the integrity of bones rendering them highly susceptible to fractures. In this article we aim to provide insight into the origins types symptoms and the spectrum of treatment options offered to individuals afflicted with Osteogenesis Imperfecta. Etiology of Osteogenesis Imperfecta. The root cause of Osteogenesis Imperfecta lies predominantly in genetic mutations affecting collagen synthesis  the pivotal protein in fortifying bone structure. Collagen plays a central role in bolstering bone integrity and any disturbances in its production render bones exceedingly brittle rendering them vulnerable to fractures. OI is generally transmitted through an autosomal dominant inheritance pattern, signifying that if one parent possesses the defective gene...