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 Paget's Disease of Bone. Symptoms Causes and Treatment Paget's disease of bone also known as osteitis deformans is a chronic medical condition that affects the normal remodeling of bone tissue. This condition is characterized by the excessive breakdown and formation of bone  leading to weakened and deformed bones. In this article we will explore the key aspects of Paget's disease including its symptoms causes and available treatment options. Symptoms of Paget's Disease The symptoms of Paget's disease can vary from person to person and some individuals may be asymptomatic. However when symptoms do occur they can include. 1. Bone Pain  One of the most common symptoms is bone pain which can be mild or severe and typically worsens with activity. 2. Deformities  Over time the affected bones can become deformed  leading to issues like bowing of long bones such as the legs and an enlarged or misshapen skull. ...